Papers

At Kansas State University:

Messer CL, Burghardt E, McDonald JA. A deficiency screen of the X chromosome for Rap1 GTPase dominant interacting genes in Drosophila border cell migration. G3 Genes|Genomes|Genetics 2025, Volume 15, Issue 5, May 2025, jkaf040, https://doi.org/10.1093/g3journal/jkaf040.

Chen Y, McDonald JA. Collective cell migration relies on PPP1R15-mediated regulation of the endoplasmic reticulum stress response. Curr Biol 2024. Apr 8;34(7):1390-1402.e4.
 doi: 10.1016/j.cub.2024.02.014. Epub 2024 Feb 29. PMID: 38428416.

Burghardt E, McDonald JA. An RNAi screen for ribosome biogenesis genes required for Drosophila border cell collective migration. microPub Biol 2024. 10.17912/micropub.biology.001292.

Burghardt E, Rakijas J, Tyagi A, Majumder P, Olson BJSC*, McDonald JA*. Transcriptome analysis reveals temporally regulated genetic networks during Drosophila border cell collective migration. BMC Genomics 2023. Dec 1;24(1):728. doi: 10.1186/s12864-023-09839-8. PMID: 38041052. *Corresponding authors.

Messer CL, McDonald JA. Rap1 promotes epithelial integrity and cell viability in a growing tissue. Dev Biol 2023. Sep:501:1-19. doi: 10.1016/j.ydbio.2023.05.006. Epub 2023 Jun 2. PMID: 37269969.

Messer CL, McDonald JA. Expect the unexpected: conventional and unconventional roles for cadherins in collective cell migration. Biochem Soc Trans 2023 Aug 31;51(4):1495-1504. doi: 10.1042/BST20221202. Review. PMID: 37387360.

Rothenberg KE, Chen Y, McDonald JA, Fernandez-Gonzalez R. Rap1 coordinates cell-cell adhesion and cytoskeletal reorganization to drive collective cell migration in vivo. Curr Biol. 2023 May 22:S0960-9822(23)00603-6. doi: 10.1016/j.cub.2023.05.009. PMID: 37244252.

Chen Y, Kotian N, McDonald JA. Quantitative Image Analysis of Dynamic Cell Behaviors During Border Cell Migration. Methods Mol Biol. 2023;2626:193-217. doi: 10.1007/978-1-0716-2970-3_10. PMID: 36715906.

N. Kotian, K.M. Troike, K.N. Curran, J.D. Lathia, J.A. McDonald. A Drosophila RNAi screen reveals conserved glioblastoma-related adhesion genes that regulate collective cell migration. Preprint on bioRxiv. G3. 2022 Volume 12, Issue 1, January 2022, jkab356, https://doi.org/10.1093/g3journal/jkab356

J.A. McDonald, Y. Tomoyasu. Extracellular Matrix: Sculpting New Structures. eLife. 2020 May 28;9:e57668. doi: 10.7554/eLife.57668. Comment. PMID: 32463359.

Y. Chen, N. Kotian, G. Aranjuez, L. Chen, C.L. Messer, A. Burtscher, K. Sawant, D. Ramel, X. Wang, J.A. McDonald. Protein Phosphatase 1 activity controls a balance between collective and single cell modes of migration. Preprint on BioRxiv. eLife. 2020;9:e52979. doi: 10.7554/eLife.52979. PMID: 32369438. PMCID: PMC7200163

Josephine Volovetz§, Artem D. Berezovsky§, Tyler Alban§, Yujun Chen, Adam Lauko, George F. Aranjuez, Ashley Burtscher, Kelly Shibuya, Daniel J. Silver, John Peterson, Danny Manor, Jocelyn A. McDonald*, Justin D. Lathia*. Identifying conserved molecular targets required for cell migration of glioblastoma cancer stem cells. Preprint on BioRxiv. §Equal contribution. *Corresponding authors. Cell Death & Disease 2020. Feb 26;11(2):152. doi: 10.1038/s41419-020-2342-2. PMID: 32102991.  PMCID: PMC7044427.

K. Sawant§, Y. Chen§, N. Kotian§, K.M. Preuss, J.A. McDonald. Rap1 GTPase promotes coordinated collective cell migration in vivo. Mol Biol Cell. 2018 Nov 1;29(22):2656-2673. doi: 10.1091/mbc.E17-12-0752. Epub 2018 Aug 29. PMID: 30156466. §Equal contribution.

X. Qin, E. Hannezo, T. Mangeat, C. Liu, P. Majumder, J. Liu, V. Cadamuro, J.A. McDonald, Y. Liu, B. Yi and X. Wang. A biochemical network controlling basal myosin oscillation. Nature Communications 9: 1210. doi:10.1038/s41467-018-03574-5. 2018.

G. Aranjuez, A. Burtscher, K. Sawant, P. Majumder* and J.A. McDonald*: Dynamic myosin activation promotes collective morphology and migration by locally balancing oppositional forces from surrounding tissue. Molecular Biology of the Cell 2016. 27(12):1898-910. doi: 10.1091/mbc.E15-10-0744. *Corresponding authors.

M.T. Veeman* and J.A. McDonald*: Dynamics of cell polarity in tissue morphogenesis: a comparative view from Drosophila and Ciona. F1000Research 2016. Jun 2; 5. pii: F1000 Faculty Rev-1084. doi: 10.12688/f1000research.8011.1. eCollection 2016. *Corresponding authors.

L.R. Klebanow, E.C. Peshel, A.T. Schuster, K. De, K. Sarvepalli, M.E. Lemieux, J.J. Lenoir, A.W. Moore, J.A. McDonald, M.S. Longworth: Drosophila Condensin II subunit, Chromosome Associated Protein-D3, regulates cell fate determination through non-cell autonomous signaling. Development 2016. 143(15):2791-802. doi: 10.1242/dev.133686.

At the Cleveland Clinic:

J.A. McDonald: Canonical and non-canonical roles for Par-1/MARK kinases in cell migration. International Review of Cell & Molecular Biology (ed. K. Jeon), 312:169-199. 2014.

B. Dickerman, J.A. McDonald and G.C. Sen: The human dsRNA binding protein PACT is unable to functionally substitute for the Drosophila dsRNA binding protein R2D2 [v2 2014; ref status: indexed, http://f1000res/352%5D. F1000Research, 2: 220. 2013. PMCID:PMC3962003.

E. R. Geisbrecht*, K. Sawant, Y. Su, C. Z. Liu, A. Burtscher, D. Silver, X. Wang, A.J. Zhu and J.A. McDonald*: Genetic interaction screens identify a role for hedgehog signaling in Drosophila border cell migration. Developmental Dynamics, 242: 414-431. 2013. PMCID:PMC3721345. *Corresponding authors.

G. Aranjuez, E. Kudlaty, M.S. Longworth and J.A. McDonald: On the role of PDZ domain-encoding genes in Drosophila border cell migration. G3: Genes/Genomes/Genetics [the open-access journal of the Genetics Society of America], 2: 1379-1391. 2012. PMCID:PMC3484668.

P. Majumder, G. Aranjuez, J. Amick and J.A. McDonald: Par-1 controls myosin-II activity through myosin phosphatase to regulate border cell migration. Current Biology, 22: 363-372. 2012. PMCID:PMC3298626.

J. A. McDonald*, A. Khodyakova, G. Aranjuez, C. Dudley, and D.J. Montell*: Par-1 kinase regulates epithelial detachment and directional protrusion of migrating border cells. Current Biology 18: 1659-1667. 2008. PMCID:PMC2593744. *Corresponding authors.

Earlier:

J.A. McDonald*§, E. Pinheiro§, L. Kadlec, T. Schupbach, and D.J. Montell*: Multiple EGFR ligands participate in guiding migrating border cells. Developmental Biology 296: 94-103. 2006. §Equal contribution; *Corresponding authors.

J.A. McDonald and D.J. Montell: On the border of understanding cell migration. In Cell Migration in Development and Disease (ed. D. Wedlich), Wiley-VCH Publications, Weinheim, Germany, pp. 123-138. 2005.

J.A. McDonald and D.J. Montell: Analysis of cell migration using Drosophila as a model system. In Cell Migration: Developmental Methods and Protocols (ed. J.-L. Guan), Methods in Molecular Biology 294: 175-202. 2005.

J.A. McDonald§, E. Pinheiro§ and D.J. Montell: PVF1, a PDGF/VEGF homolog, is sufficient to guide the border cells and genetically interacts with Taiman. Development 130: 3469-3478. 2003. §Equal contribution.

J.A. McDonald, M. Fujioka, J. Odden, J. B. Jaynes and C. Q. Doe: Specification of motoneuron fate in Drosophila: Integration of positive and negative transcription factor inputs by a minimal eve enhancer. Journal of Neurobiology 57:193-203. 2003.

J.A. McDonald, S. Holbrook, T. Isshiki, J. Weiss, C.Q. Doe and D. Mellerick: Dorsoventral patterning in the Drosophila central nervous system: The vnd homeobox gene specifies ventral column identity. Genes & Development 12: 3603-3612. 1998.

J.A. McDonald and C.Q. Doe: Establishing neuroblast-specific gene expression in the Drosophila CNS: huckebein is activated by Wingless and Hedgehog and repressed by Engrailed and Gooseberry. Development 124: 1079-1087. 1997.

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